Discover dr.he Metabolyn™ PRO, The Next-Gen Probiotic
Formulated with probiotic AKK plus 5 unique, multi-patented ‘crown’ strains, (CLA) and prebiotics. This advanced formula is powered by metabolic research to support a balanced gut microbiome and healthy metabolic function, digestion, mood and overall wellbeing. Delivers real, research-backed results.
Supports healthy weight management, gut health, metabolism, and mood.
Features crown strains: scientifically selected probiotics with superior stability and targeted benefits.
Developed with Dr. Eugene He, renowned expert in nutraceutical research and naturopathic medicine.
In collaboration with Bioflag (Asia’s leading probiotic research group).
Who is dr.he Metabolyn™ PRO for?
dr.he Metabolyn™ PRO is formulated for adults looking to support their gut health, metabolism, and overall well-being. It’s ideal for:
Individuals seeking weight management support through improved metabolism and gut balance.
People experiencing digestive discomfort like bloating or sluggish digestion.
Those looking for enhanced mood, better sleep, and stress reduction as part of their wellness routine.
Adults with busy lifestyles who want a probiotic formula backed by science to improve energy and support long-term health.
Anyone looking to optimize their gut microbiome and boost immunity naturally.
The Science Behind dr.he Metabolyn™ PRO
Probiotic Strain
Function
Akkermansia muciniphila AMY001 (AKK)
Helps strengthen gut lining, supports metabolic health
Bifidobacterium breve B-3
Supports fat metabolism & healthy weight management
Lactobacillus paracasei K56
Helps reduce stress & supports restorative sleep
Bifidobacterium animalis CP-9
Supports digestion & gut-brain communication
Bifidobacterium lactis BL-99
Supports gut function, lipid metabolism & athletic performance
Bifidobacterium breve CCFM1025
Supports mental well-being & mood balance
Backed Clinical Studies
1. Weight Management & Fat Reduction
B-3 probiotic reduced body fat by 0.6 kg and fat % by 0.7% after 12 weeks.¹ ² ³
AKK supplementation resulted in significant reductions in body fat and weight after 12 weeks in individuals with type 2 diabetes.⁴
2. Digestive Comfort
BL-99 significantly improved functional dyspepsia (indigestion) symptoms to 90% vs 58% in placebo.⁵
3. Immunity & Microbiome Balance
CP-9 accelerated bilirubin clearance in infants, demonstrating systemic gut benefits.⁶
4. Mood & Mental Health
K56 led to a significant reduction in anxiety and improved sleep scores.⁷ ⁸
CCFM1025 improved depression scores in MDD patients in 4 weeks.⁹ ¹⁰
What Makes dr.he Metabolyn™ PRO Different?
A new class of probiotics – powered by crown strains and metabolic research.
Feature
Generic Probiotics
dr.he Metabolyn™ PRO
Generic probiotic strains
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Targets digestion only
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Crown strains with metabolic effects
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Supports GLP-1 production for fat breakdown
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Enhances sleep & mood
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Reduces visceral fat & waist size
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Directions of Use
Take 1 sachet daily, directly into the mouth or mix with cool water. Best taken after meals.
Safe for adults 16+.
Suitable for long-term use.
References:
Minami J, Iwabuchi N, Tanaka M, et al. Effects of Bifidobacterium breve B-3 on body fat reductions in pre-obese adults: a randomized, double-blind, placebo-controlled trial. Biosci Microbiota Food Health. 2018;37(3):67-75. doi:10.12938/bmfh.18-001
Sung HK, Youn SJ, Choi Y, Eun SW, Shin SM. Body Fat Reduction Effect of Bifidobacterium breve B-3: A Randomized, Double-Blind, Placebo Comparative Clinical Trial. Nutrients. 2022;15(1):28. doi:10.3390/nu15010028
Minami J, Kondo S, Yanagisawa N, et al. Oral administration of Bifidobacterium breve B-3 modifies metabolic functions in adults with obese tendencies in a randomised controlled trial. J Nutr Sci. 2015;4:e17. doi:10.1017/jns.2015.5
Zhang Y, Liu R, Chen Y, et al. Akkermansia muciniphila supplementation in patients with overweight/obese type 2 diabetes: Efficacy depends on its baseline levels in the gut. Cell Metab. 2025. Advance online publication. doi:10.1016/j.cmet.2024.12.010
Zhang Q, Li G, Zhao W, et al. Efficacy of Bifidobacterium animalis subsp. lactis BL-99 in the treatment of functional dyspepsia: a randomized placebo-controlled clinical trial. Nat Commun. 2024;15:227. doi:10.1038/s41467-023-44292-x
Tsai ML, Lin WY, Chen YT, et al. Adjuvant probiotic Bifidobacterium animalis subsp. lactis CP-9 improves phototherapeutic treatment outcomes in neonatal jaundice. Medicine. 2022;101(45):e31030. doi:10.1097/MD.0000000000031030
He J, et al. Effects of Lacticaseibacillus paracasei K56 on perceived stress among pregraduate students: a double-blind, randomized, placebo-controlled trial. Front Nutr. 2025. doi:10.3389/fnut.2025.1544713
Kadeer G, Fu W, He Y, et al. Effect of different doses of Lacticaseibacillus paracasei K56 on body fat and metabolic parameters in adult individuals with obesity: a pilot study. Nutr Metab (Lond). 2023;20:16. doi:10.1186/s12986-023-00739-y
Tian P, Chen Y, Zhu H, et al. Bifidobacterium breve CCFM1025 attenuates major depression disorder via regulating gut microbiome and tryptophan metabolism: A randomized clinical trial. Brain Behav Immun. 2022;100:233-241. doi:10.1016/j.bbi.2021.11.023
Lan Y, Lu J, Qiao G, et al. Bifidobacterium breve CCFM1025 Improves Sleep Quality via Regulating the Activity of the HPA Axis: A Randomized Clinical Trial. Nutrients. 2023;15(21):4700. doi:10.3390/nu15214700