[10.10] 10x Protocol X V3

Essential+ Methylated Multivitamin Xandro Essential+ is a science-backed daily multivitamin and mineral formula designed for superior absorption and long-term health support. Unlike generic multivitamins, Essential+ uses activated, methylated vitamins and clinically-validated mineral chelates to maximize bioavailability and efficacy. The formula is intentionally free of herbal extracts, fillers, and non-essential additives, focusing on clinically validated, bioactive nutrients that the body can readily use. It is also vegan-friendly, with plant-based vitamin D3, B12, and seaweed-derived calcium. Who Should Try Essential+? Adults 18 and above seeking foundational daily health support Anyone focused on proactive health—supporting energy, cellular renewal, brain clarity, immunity, and heart health Vegans and clean-label consumers looking for bioavailable nutrients without fillers or herbal extracts Why Methylation Matters? Many generic multivitamins uses synthetic folic acid and inactive B vitamins that must be converted in the body before they’re usable. However, up to 40% of people have MTHFR gene variants that reduce this conversion efficiency—leading to poor absorption and unmetabolized folic acid buildup. Xandro Essential+ uses 5-MTHF directly—the bioactive, ready-to-use form—making it more effective and better absorbed. This is a key differentiator between generic and premium multivitamins. What Makes 5-MTHF So Special? Essential+ uses 5-MTHF (5-methyltetrahydrofolate) — the biologically active form of folate (vitamin B9); and not synthetic folic acid. This allows for superior absorption, and plays a vital role in: Energy production through efficient methylation Cognitive performance and mood regulation Cardiovascular health by supporting homocysteine balance Cellular renewal and healthy aging What Makes Essential+ Different from Standard Multivitamins?  ✓ Methylated nutrients for superior absorption ✓ 5-MTHF – the active folate your body uses immediately ✓ Seaweed-derived calcium for natural bioavailability ✓ No herbal extracts = lower risk of unwanted reactions ✓ Built for long-term healthspan, not just today ✓ Independently tested for purity and potency ✓ Made in GMP & HACCP-certified facilities How Essential+ Compares Feature Essential+ Standard Multivitamin Methylated Nutrients ✔ Yes – Active forms like 5-MTHF folate  ✖ No – Synthetic folic acid Bioavailable Mineral Forms ✔ Gluconate and seaweed-derived ✖ Often poorly absorbed oxides or sulfates Full-Spectrum Formula ✔ Includes all essential vitamins + trace minerals ✖ May skip key micronutrients Allergen-Friendly ✔ No herbal extracts ✖ Often includes blends that may trigger sensitivities Longevity-Focused ✔ Supports energy, mood, cell renewal & aging ✖ Generalised support only Built for synergy ✔ Nutrients that work together ✖ Random combos Third-Party Tested ✔ Independently verified for quality ✖ Often unverified claims Made in GMP & HACCCP Facility ✔ Yes ✖ Not always disclosed How To Take Essential+  Take 1 tablet daily with water, with or after food. Can be combined with other Xandro products like Protocol X or Joint Recovery without risk of overlapping active ingredients.

Xandro Joint Recovery is your daily solution for maximum joint support: fast, safe, relief, backed by scientific studies. Powered by next-generation, highest quality natural ingredients – Mangoselect® and SCP-II Proteoglycan. It is designed to ease discomfort, restore mobility and support long-term joint and cartilage health and function. Feel real results in just 5 days, so you can get back to the things you love. Natural and safe, Mangoselect® from mangosteen and SCP-II salmon proteoglycan support mobility, healthy joint function  and comfort – without side effects. Ideal for users with active lifestyles and seeking healthy aging. Who Should Try Xandro Joint Recovery? Anyone with joint stiffness or discomfort Runners, gym-goers, athletes and active people looking to protect their joints Aging adults who want to stay mobile and comfortable Menopausal and post-menopausal women, as hormonal changes can weaken joints How It Works: The Science Behind Xandro Joint Recovery Xandro Joint Recovery is a scientifically advanced supplement formulated to help relieve joint discomfort and support mobility and long-term joint health – without the need for NSAIDs (nonsteroidal anti-inflammatory drugs) or harsh chemicals. Studies show results in as little as 5 days, this innovative formula combines two powerhouse ingredients: 1. Mangoselect®: Nature’s powerful anti-inflammatory Key findings of Mangostreen extract: Reduces joint pain by 37.4% in just 5 days¹ Blocks key inflammation markers: TNF-α, COX-2, PGE2² Increases antioxidant levels to help protect cartilage from further damage³ 2. SCP-II Proteoglycan: Repairs & Lubricates Joints  Key findings of SCP-II Proteoglycan:  Stimulates cartilage regeneration for sustainable joint health and flexibility⁴ Clinically shown to reduce knee pain by 30%⁵ Improves joint mobility by 25%, based on WOMAC score⁵ (See FAQ) Synergistic Benefits Together, they work to not just manage symptoms, but rebuild resilience. When combined, these ingredients deliver faster relief from joint discomfort and support joint health and mobility than conventional options like glucosamine or chondroitin. You don’t just feel better – you move better and stay that way. What You’ll Notice Less stiffness when you wake up Easier movement throughout the day More confidence in your knees, hips and joints Long-term support without NSAIDs or synthetic fillers Xandro Joint Recovery vs Traditional Joint Supplements Absorption Xandro Joint Recovery Glucosamine & Chondroitin NSAIDs Time to Relief As little as 5 days 4–8 weeks 1–2 hours Supports Healthy Cartilage and Mobility ✔ ✔ ✘ Natural & Drug-Free ✔ ✔ ✘ Long-Term Safety ✔ ✔ ✘ (risk of side effects) No Harsh Side Effects ✔ ✔ ✘ (stomach, kidney, liver risks) Why Choose Xandro Joint Recovery Over Glucosamine, Chondroitin or Turmeric? Fast-acting results in just 5 days Ingredients supported by scientific studies Naturally sourced and drug-free No NSAIDs, no harsh chemicals Gluten-free, Dairy-free, Non-GMO Artificial colors or flavoring, preservatives or additives Supports long-term joint health, not just pain masking discomfort   How to Use Take two capsules a day: 1 in the morning and 1 in the evening, with water, preferably after a meal. For optimal results, use consistently and pair with light mobility exercises or physical therapy routines.   Good to know Not suitable for people with fish allergies, vegetarians or vegans as it contains fish.   References Romain C, Cases J. Mangosteen extract for short-term pain management: Preclinical approach and pilot clinical investigation on volunteers with soft tissue pain. Agro Food Ind Hi Tech. 2015;26(3):8-10. https://www.researchgate.net/publication/279057657_Mangosteen_extract_for_short-term_pain_management_-_Preclinical_approach_and_pilot_clinical_investigation_on_volunteers_with_soft_tissue_pain  Nakatani K, et al. Inhibition of cyclooxygenase and prostaglandin E2 synthesis by gamma-mangostin, a xanthone derivative in mangosteen, in C6 rat glioma cells. Biochem Pharmacol. 2002;63(1):73-79. https://www.sciencedirect.com/science/article/abs/pii/S0006295201008103?via%3Dihub   Kondo M, et al. Bioavailability and antioxidant effects of a xanthone-rich Mangosteen (Garcinia mangostana) product in humans. J Agric Food Chem. 2009;57(19):8788-8792. https://pubs.acs.org/doi/10.1021/jf901012f Kuriyama Y, et al. Effects of taking salmon nasal cartilage extract (containing undenatured type II collagen and undenatured proteoglycan) on knee joint pain. J New Rem & Clin. 2016;65(11). https://www.spandidos-publications.com/10.3892/etm.2017.4454 Kuriyama Y, et al. Effects of Salmon Nasal Cartilage Extract Powder Standardized Undenatured Type II Collagen and Proteoglycan on Knee Pain in Healthy Volunteers—A Single Center Randomized, Double-blind, Placebo-controlled Study—: Re-analysis results focused on the knee with stronger pain. Jpn Pharmacol Ther. 2020;48(11). https://www.spandidos-publications.com/10.3892/etm.2017.4454

What is NMN? NMN (Nicotinamide Mononucleotide) is a Vitamin B3 derivative. It is also a direct precursor of NAD+ (Nicotinamide Adenine Dinucleotide), which is integral for cellular energy production in our bodies. NMN is integral to boosting NAD+ levels, which in turns helps with boosting our energy levels. ☑️ Promote Metabolic Health ☑️ Support Healthy Ageing ☑️ Promote Overall Vitality   What makes Xandro Lab Pure NMN Capsules better? Made in a GMP-Certified facility High purity, above 99% pure NMN.   Pure NMN Powder Vs Pure NMN Capsules. What is better for me?   Pure NMN Capsule Pure NMN Powder Absorption Extended release Fast release Taste No taste Slightly sour Stability Protected from environmental factors such as humidity, high temperature and dust. Okay in ambient temperature Convenience Easy to carry during travel. Easy to store. No need to measure serving size.  Can be added to food or drinks for ease of use.  Serving size can be tweaked. Dosage Consistency Capsules generally offer a consistent dosage. With powder, you can adjust the dosage more freely based on personal needs.  Contamination Low risk Careful storage advised to prevent dust or contaminants. Dosage 500 mg (1 capsule) 500 mg (⅓ scoop) Price SGD 116 SGD 95   Did you know? Produced naturally in our bodies, NMN is also found in fruits and vegetables like broccoli and avocado. You only need to consume 1 capsule of NMN daily to feel more energized than ever. Why supplement with NMN? As we get older, NAD+ in our body falls rapidly. By age 40, NAD+ can decline by as much as 50%. [1] Scientific Evidence 1) Aerobic capacity during exercise is improved following 6 weeks of NMN consumption with doses ranging from 300 to 1200 mg/day. [2] 2) The study findings suggest that a daily oral intake of 1250 mg of NMN for a maximum of 4 weeks is well-tolerated and safe for healthy men and women. [3] 3) NMN supplementation in the afternoon improved lower limb function and reduced drowsiness in older adults, indicating that it may help to maintain physical well-being and alleviate fatigue in this population. [4]   Directions of use Take 1 capsule daily with food preferably during morning or afternoon for all day energy. If you are pregnant or nursing or have a known medical condition, consult a physician before use.   **Additional Information to note: NMN is sensitive to moisture and high temperature, so we recommend that NMN be stored in a cool and dry environment. ☑️ 60 capsules ☑️ 500mg per capsule ☑️ Manufactured in a GMP-Certified Facility in Singapore ☑️ Third-party lab tested for purity   References McReynolds MR, Chellappa K, Baur JA. Age-related NAD+ decline. Exp Gerontol. 2020 Feb 22;134:110888. doi: 10.1016/j.exger.2020.110888. Epub ahead of print. PMID: 32097708; PMCID: PMC7442590. Liao, B., Zhao, Y., Wang, D. et al. Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study. J Int Soc Sports Nutr 18, 54 (2021). https://doi.org/10.1186/s12970-021-00442-4 Fukamizu, Y., Uchida, Y., Shigekawa, A. et al. Safety evaluation of β-nicotinamide mononucleotide oral administration in healthy adult men and women. Sci Rep 12, 14442 (2022). https://doi.org/10.1038/s41598-022-18272-y Kim M, Seol J, Sato T, Fukamizu Y, Sakurai T, Okura T. Effect of 12-Week Intake of Nicotinamide Mononucleotide on Sleep Quality, Fatigue, and Physical Performance in Older Japanese Adults: A Randomized, Double-Blind Placebo-Controlled Study. Nutrients. 2022 Feb 11;14(4):755. doi: 10.3390/nu14040755. PMID: 35215405; PMCID: PMC8877443.

Discover dr.he Metabolyn™ PRO, The Next-Gen Probiotic Formulated with probiotic AKK plus 5 unique, multi-patented ‘crown’ strains, (CLA) and prebiotics. This advanced formula is powered by metabolic research to support a balanced gut microbiome and healthy metabolic function, digestion, mood and overall wellbeing. Delivers real, research-backed results. Supports healthy weight management, gut health, metabolism, and mood. Features crown strains: scientifically selected probiotics with superior stability and targeted benefits. Developed with Dr. Eugene He, renowned expert in nutraceutical research and naturopathic medicine. In collaboration with Bioflag (Asia’s leading probiotic research group). Who is dr.he Metabolyn™ PRO for? dr.he Metabolyn™ PRO is formulated for adults looking to support their gut health, metabolism, and overall well-being. It’s ideal for: Individuals seeking weight management support through improved metabolism and gut balance. People experiencing digestive discomfort like bloating or sluggish digestion. Those looking for enhanced mood, better sleep, and stress reduction as part of their wellness routine. Adults with busy lifestyles who want a probiotic formula backed by science to improve energy and support long-term health. Anyone looking to optimize their gut microbiome and boost immunity naturally. The Science Behind dr.he Metabolyn™ PRO Probiotic Strain Function Akkermansia muciniphila AMY001 (AKK) Helps strengthen gut lining, supports metabolic health Bifidobacterium breve B-3 Supports fat metabolism & healthy weight management Lactobacillus paracasei K56 Helps reduce stress & supports restorative sleep Bifidobacterium animalis CP-9 Supports digestion & gut-brain communication Bifidobacterium lactis BL-99 Supports gut function, lipid metabolism & athletic performance Bifidobacterium breve CCFM1025 Supports mental well-being & mood balance Backed Clinical Studies 1. Weight Management & Fat Reduction B-3 probiotic reduced body fat by 0.6 kg and fat % by 0.7% after 12 weeks.¹ ² ³ AKK supplementation resulted in significant reductions in body fat and weight after 12 weeks in individuals with type 2 diabetes.⁴ 2. Digestive Comfort BL-99 significantly improved functional dyspepsia (indigestion) symptoms to 90% vs 58% in placebo.⁵ 3. Immunity & Microbiome Balance CP-9 accelerated bilirubin clearance in infants, demonstrating systemic gut benefits.⁶ 4. Mood & Mental Health K56 led to a significant reduction in anxiety and improved sleep scores.⁷ ⁸ CCFM1025 improved depression scores in MDD patients in 4 weeks.⁹ ¹⁰ What Makes dr.he Metabolyn™ PRO Different? A new class of probiotics – powered by crown strains and metabolic research. Feature Generic Probiotics dr.he Metabolyn™ PRO Generic probiotic strains ✔ ✔ Targets digestion only ✔ ✘ Crown strains with metabolic effects ✘ ✔ Supports GLP-1 production for fat breakdown ✘ ✔ Enhances sleep & mood ✘ ✔ Reduces visceral fat & waist size ✘ ✔   Directions of Use Take 1 sachet daily, directly into the mouth or mix with cool water. Best taken after meals.  Safe for adults 16+. Suitable for long-term use.   References:  Minami J, Iwabuchi N, Tanaka M, et al. Effects of Bifidobacterium breve B-3 on body fat reductions in pre-obese adults: a randomized, double-blind, placebo-controlled trial. Biosci Microbiota Food Health. 2018;37(3):67-75. doi:10.12938/bmfh.18-001 Sung HK, Youn SJ, Choi Y, Eun SW, Shin SM. Body Fat Reduction Effect of Bifidobacterium breve B-3: A Randomized, Double-Blind, Placebo Comparative Clinical Trial. Nutrients. 2022;15(1):28. doi:10.3390/nu15010028 Minami J, Kondo S, Yanagisawa N, et al. Oral administration of Bifidobacterium breve B-3 modifies metabolic functions in adults with obese tendencies in a randomised controlled trial. J Nutr Sci. 2015;4:e17. doi:10.1017/jns.2015.5 Zhang Y, Liu R, Chen Y, et al. Akkermansia muciniphila supplementation in patients with overweight/obese type 2 diabetes: Efficacy depends on its baseline levels in the gut. Cell Metab. 2025. Advance online publication. doi:10.1016/j.cmet.2024.12.010 Zhang Q, Li G, Zhao W, et al. Efficacy of Bifidobacterium animalis subsp. lactis BL-99 in the treatment of functional dyspepsia: a randomized placebo-controlled clinical trial. Nat Commun. 2024;15:227. doi:10.1038/s41467-023-44292-x Tsai ML, Lin WY, Chen YT, et al. Adjuvant probiotic Bifidobacterium animalis subsp. lactis CP-9 improves phototherapeutic treatment outcomes in neonatal jaundice. Medicine. 2022;101(45):e31030. doi:10.1097/MD.0000000000031030 He J, et al. Effects of Lacticaseibacillus paracasei K56 on perceived stress among pregraduate students: a double-blind, randomized, placebo-controlled trial. Front Nutr. 2025. doi:10.3389/fnut.2025.1544713 Kadeer G, Fu W, He Y, et al. Effect of different doses of Lacticaseibacillus paracasei K56 on body fat and metabolic parameters in adult individuals with obesity: a pilot study. Nutr Metab (Lond). 2023;20:16. doi:10.1186/s12986-023-00739-y Tian P, Chen Y, Zhu H, et al. Bifidobacterium breve CCFM1025 attenuates major depression disorder via regulating gut microbiome and tryptophan metabolism: A randomized clinical trial. Brain Behav Immun. 2022;100:233-241. doi:10.1016/j.bbi.2021.11.023 Lan Y, Lu J, Qiao G, et al. Bifidobacterium breve CCFM1025 Improves Sleep Quality via Regulating the Activity of the HPA Axis: A Randomized Clinical Trial. Nutrients. 2023;15(21):4700. doi:10.3390/nu15214700

What is Turmeric Curcumin? Turmeric is a spice that has been used for centuries for its health-related benefits. The active ingredient in turmeric is curcumin, a compound with powerful antioxidant and anti-inflammatory effects. ☑️ Anti-Inflammation & Relieve Joint Pains ☑️ Aid In Blood Sugar Control ☑️ Improve Digestive Health ☑️ Help Reduce Cholesterol   What makes Xandro Lab Turmeric Curcumin better? Curcumin's bioavailability is relatively low when consumed on its own, and it can be challenging for the body to absorb. Xandro Lab’s uses patented BCM-95 Turmeric Curcumin, which has high bioavailability. BCM-95 is a 100% pure turmeric extract that boasts enhanced bio-efficacy. Did you know? While turmeric contains curcumin, the curcumin content in raw turmeric is relatively low, usually around 2-5% by weight. It's low natural curcumin bioavailability has led to enhanced formulations to improve its absorption for potential health benefits. BCM-95’s composition makes it the world’s most natural turmeric extract, with free curcumin scientifically proven to be retained in the bloodstream even after 8 hours. The ‘95’ in its name represents the patented composition of this potent 95% standardized curcumin-essential oil complex (CEC) Why supplement with Tumeric Curcumin? As we age, inflammation & sustained joint pains can become growing concerns for our health. Turmeric Curcumin, backed by traditional health practices, emerges as a solution to address the inflammatory processes associated with aging. By actively combating inflammation and supporting cellular rejuvenation, it plays a vital role in promoting healthy mobility & aging. Scientific Evidence 1) Current research indicates that inflammation, oxidative stress, and many long-term conditions are closely interconnected. Curcumin's antioxidant properties can play a vital role in boosting our overall well-being and healthy aging¹. 2) Curcumin exhibits greater impact in pain reduction and enhancing functional ability compared to traditional joint supplements, as indicated by effect sizes (ES)². 3) A 9-month curcumin study involving 240 participants suggested potential benefits in blood glucose regulation in individuals while improving their β-cell function³. 4) Research has indicated that curcumin affects the gut microbiome and exerts neuroprotective effects through the microbiota-gut-brain axis (MGB)⁴.   Directions of use Take 1 capsule twice daily with food, preferably in the morning & evening. If you are pregnant or nursing or have a known medical condition, consult a physician before use. ☑️ 30 capsules ☑️ 400mg per capsule ☑️ Manufactured in a GMP-Certified Facility in Singapore ☑️ Third-party lab tested for purity   References:  Izadi M, Sadri N, Abdi A, Zadeh MMR, Jalaei D, Ghazimoradi MM, Shouri S, Tahmasebi S. Longevity and anti-aging effects of curcumin supplementation. Geroscience. 2024 Jun;46(3):2933-2950. doi: 10.1007/s11357-024-01092-5. Epub 2024 Feb 27. PMID: 38409646; PMCID: PMC11009219. Paultre K, Cade W, Hernandez D, Reynolds J, Greif D, Best TM. Therapeutic effects of turmeric or curcumin extract on pain and function for individuals with knee osteoarthritis: a systematic review. BMJ Open Sport Exerc Med. 2021 Jan 13;7(1):e000935. doi: 10.1136/bmjsem-2020-000935. PMID: 33500785; PMCID: PMC7812094. Chuengsamarn S, Rattanamongkolgul S, Luechapudiporn R, Phisalaphong C, Jirawatnotai S. Curcumin extract for prevention of type 2 diabetes. Diabetes Care. 2012 Nov;35(11):2121-7. doi: 10.2337/dc12-0116. Epub 2012 Jul 6. PMID: 22773702; PMCID: PMC3476912. Di Meo F, Margarucci S, Galderisi U, Crispi S, Peluso G. Curcumin, Gut Microbiota, and Neuroprotection. Nutrients. 2019 Oct 11;11(10):2426. doi: 10.3390/nu11102426. PMID: 31614630; PMCID: PMC6835970.

New LPC Neuro is set to revolutionise your brain wellness. Our next-generation breakthrough in brain and eye health is powered by Lysoveta™, the world’s most advanced omega-3 supplement. The Science Behind LPC Neuro As we age, oxidative stress damages the membranes of the brain's neurons, causing cognitive decline, memory loss, and learning difficulties. Lysophosphatidylcholine-DHA and -EPA (LPC-DHA and LPC-EPA), trademarked as Lysoveta™, are groundbreaking omega-3 lipids that support brain health and slow cognitive ageing. It is the active ingredient in LPC Neuro. Pure and Sustainable Ingredients: Each LPC Neuro gel cap is filled with LPC-Rich Oil: Sustainably sourced from Antarctic krill, LPC-bound DHA and EPA The Krill extract is rigorously tested for purity, free from heavy metals and contaminants. HALAL Friendly but Not Vegan – Capsule made with bovine gelatine. Key Benefits of Lysoveta™: ☑️ Most bioavailable omega-3 supplement ☑️ Crosses the blood-brain barrier to deliver critical DHA, EPA and choline ☑️ Restores and protects neuron membranes ☑️ Enhances memory, focus and cognitive clarity Key Features of LPC Neuro: Superior Absorption: Most bioavailable form of omega-3. Targeted Brain Support: Crosses the blood-brain barrier to deliver essential DHA, EPA, and choline. Neuron Care: Helps maintain and protect brain cell membrane structures. Mental Clarity: Supports sharper memory, improved focus, and cognitive clarity. What Sets Lysoveta™ Apart Revolutionary Ingredient: Lysoveta™ LPC-bound EPA/DHA delivers essential omega-3s (DHA and EPA) and choline directly to the brain and eyes. Blood-Brain Barrier Penetration: Unlike standard omega-3s, Lysoveta™ is already in its final form for direct delivery to the brain, crossing the blood-brain barrier via the Mfsd2a protein. Neuronal Support: Replenishes and renews neuron membranes, protecting them against daily oxidative stress. Cognitive Benefits: Supports sharper thinking, better memory, and long-term cognitive vitality. How To Use LPC Neuro Take one softgel daily in the morning with water. Can be taken with or without food. Safety Notice: Consult your healthcare provider before use if pregnant, nursing, or taking blood thinners. LPC Neuro is not suitable for people with shellfish allergies. It is HALAL Friendly but Not Vegan – Capsule made with bovine gelatine.   Serving Size: 1 Softgel | 30 Softgel per Pack